This study investigates the relationship between Burnout Syndrome and Quality of Professional Life in employees of accounting offices. It is a descriptive study with a quantitative approach, through a survey with accountants working in accounting firms in Southwest Paraná. The Copenhagen burnout Inventory (CBI) and Qualidade de Vida Professional (QVP-35 – Quality of Professional Life) questionnaire were used. Analyzing the correlations between the variables, the results showed low correlation rates: the constructs of burnout showed a moderate significant positive correlation with each other. However, when correlated with the dimensions of Quality of Professional Life, the results indicated, in most cases, a low significant negative correlation, highlighting the correlations between the three burnout dimensions and the Quality of Professional Life factors "Work-Related Discomfort" and "Intrinsic Motivation". The academic contribution of this study is initial evidence of the relationship between the variables investigated, with a focus on accounting professionals in Brazil, contributing to the composition of a study agenda on the subject.