The advancement of information and communication technologies and molecular biology in the late 20th and early 21st centuries created a new economy and politics of signs, reconfiguring Michel Foucault's concept of biopolitics. Human life is now produced and subjectified by new languages, based on biomolecules and algorithms, which promote new ways of storing and projecting existence. In this context, the "1st Brazilian Congress on Life Policies in the Digital Age" was held at UNIVALI to discuss these transformations. The event, which included conferences and roundtables, sought to deepen the understanding of how digitalization and biotechnological advances impact the construction of subjects and modes of government. Organized in partnership with research groups from UNIVALI, UFS, and UFSC, the congress is part of a broader project that investigates new manifestations of biopolitics, such as the transmutation of the "self" into a "profile" and the creation of organisms through biotechnology. The event also aimed to create research networks and interinstitutional partnerships for the production of scientific papers. The dossier presented here brings together the debates held, highlighting the urgency of critical discussions on how surveillance capitalism and algorithmic governmentality shape life in its biomolecular and digital dimensions.